diff (short for Clostridioides difficile, formerly Clostridium difficile) is a bacterium that causes severe diarrhea and inflammation of the colon (colitis). This infection most often occurs after the use of antibiotics that disrupt the normal balance of bacteria in your intestines.
According to the Centers for Disease Control and Prevention (CDC), C. diff causes nearly half a million infections in the United States each year. About 1 in 6 patients who get a C. diff infection will experience another episode within 2 to 8 weeks.
Common Symptoms
C. diff symptoms can range from mild to severe and may include:
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- Watery diarrhea (three or more times per day for several days)
- Abdominal pain or cramping
- Fever
- Nausea and loss of appetite
- Dehydration
- In severe cases, colitis and life-threatening intestinal inflammation
If you develop these symptoms-especially after taking antibiotics-it’s important to seek medical care immediately.
Treatment Options at IDATB
If you are experiencing C. diff infection, Infectious Disease Associates of Tampa Bay (IDATB) offers expert diagnosis and treatment.
Our team provides:
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- Comprehensive evaluation and stool testing for confirmation
- Evidence-based antibiotic therapy targeting C. diff bacteria
- Guidance on restoring healthy gut flora through probiotics and nutritional advice
- Additional treatment options for those with recurrent C. diff infection
- Access to research studies and clinical trials exploring new treatment options
Our infectious disease specialists have years of experience treating recurrent and complex C. diff infections and can help prevent recurrence through tailored care plans.
Preventing C. diff Recurrence
Preventive measures include:
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- Using antibiotics only when medically necessary
- Practicing good hand hygiene with soap and water (hand sanitizer alone may not kill C. diff spores)
- Cleaning household surfaces with bleach-based disinfectants if someone in your home is infected
- Avoiding unnecessary stomach acid medications unless prescribed
For detailed prevention guidance, visit the CDC resource.
Why Choose IDATB
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- Board-Certified Infectious Disease Experts with decades of clinical experience
- Access to the latest treatments and clinical research trials
- Comprehensive care from diagnosis through recovery
- Trusted by Tampa Bay hospitals and providers for infection management
Get Help for C. diff Today
If you’re experiencing symptoms of C. diff or have had a recurrence, contact us at (813) 251-8444 to schedule an appointment.
Our specialists serve patients across Tampa, Wesley Chapel, and the greater Tampa Bay area, providing advanced care in a comfortable outpatient setting.